The Washington Manual of Medical Therapeutics

Tartalom

Preface XV
Yoon Kang and Alison J. Whelan 1 Patient Care in Internál Medicine General Care of the Hospitalized Patient 1 1
Acute Inpatient Care 2
Sedative and Psychoactive Drug Therapy 7
Therapy of Surgical Patients 16
General Eye Care 20
Dermatologic Therapy 23
Sámuel Klein 2 Nutritional Therapy 27
Gary G. Singer 3 Fluid and Electrolyte Management 43
General Management of Fluids 43
Salt and Water 44
Potassium 53
Calcium 60
Phosphorus 66
Magnesium 68
Acid-Base Disturbances 69
Aubrey R. Morrison 4 Hypertension 76
Defmitions and Diagnostic Evaluation 76
Therapeutic Considerations 78
Special Considerations 93
Stacy C. Smith and
Anne C. Goldberg
Ischemic Heart Disease 96
Primary Prevention 96
Stable Angina 97
Unstable Angina and Non-ST- 103
Elevation Myocardial Infarction
ST-Elevation Myocardial Infarction 105
Subsequent Management of 114
Myocardial Infarction
Complications of Myocardial Infarction 116
Silent Ischemia 124
Coronary Vasospasm and Variant 124
Angina
Secondary Prevention 125
Hyperlipidemia in Patients 126
with Ischemic Heart Disease
Gregory A. Ewald and
Joseph G. Rogers
Heart Failure, Cardiomyopathy,
and Valvular Heart Disease
Heart Failure
Cardiomyopathy
Pericardial Disease
Valvular Heart Disease
131
131
143
146
147
Mitchell N. Faddis
Michael Lippmann
Cardiac Arrhythmias 153
Recognition and Diagnosis 153
Mechanisms of Arrhythmia 157
Treatment 163
Antiarrhythmic Drug Therapy 167
8
Cardiopuimonary Resuscitation
and Advanced Cardiac
Life Support
Basic Life Support
General Considerations of Advanced
Cardiac Life Support
Specifíc Arrest Sequences in
Advanced Cardiac Life Support
Postresuscitation Management
Common Medications Used in
Advanced Cardiac Life Support
181
181
182
184
192
192
Marin H. Kollef 9 Critical Care 195
Respiratory Failure 195
Oxygen Therapy 197
Airway Management and Tracheal Intubation 198
Mechanical Ventilation 201
Shock 210
Hemodynamic Monitoring and Pulmonary Artery Catheterization 213
10
Subramanian Paranjothi and Pulmonary Diseases 216
Dan Schuller Pulmonary Symptoms 216
Pleural Effusion 218
Chronic Obstructive 221
Pulmonary Disease
Cystic Fibrosis 228
Pulmonary Embolism 230
Pulmonary Aspiration Syndromes and Lung Abscess 233
Interstitial Lung Disease 234
Pulmonary Hypertension 238
Sleep Apnea Syndrome 239
Anne Pittman and 11 Allergy and Immunology 241
Mario Castro Drug Reactions 241
Anaphylaxis 243
Asthma 245
Urticaria and Angioedema 251
Immunodeficiency 254
12
Shubhada N. Ahya and Renal Diseases 256
Dániel W. Coyne Evaluation of the Patient with Renal Disease 256
Acute Renal Failure 258
Glomerulonephropathies 263
Chronic Renal Failure 267
Renal Replacement Therapies 270
Nephrolithiasis 273
Raymond M. Johnson and
Dávid J. Ritchie
Linda M. Mundy
13
Aritimicrobials
Antibacterial Agents
Antituberculous Agents
Antiviral Agents
Antifungal Agents
14
Treatment of Infectious
Diseases
Principles of Therapy
Fever and Rash
Sepsis
Catheter-Related Infections
Meningitis
Infective Endocarditis
Respiratory Tract Infections
Gastrointestinal and
Abdominal Infections
Skin, Soft-Tissue, and
Bone Infections
Genitourinary Infections
Toxin-Mediated Infections
Sexually Transmitted Diseases
Tuberculosis
Systemic Mycoses
Zoonoses and Arthropod-Borne
Diseases
Humán and Animál Bites
Woraphot Tantisiriwat and
Pablo Tebas
15
HIV Infection and AIDS
275
275
288
289
291
294
294
295
296
297
298
300
304
307
308
310
312
313
316
319
321
324
327
16
Brent W. Miller and Transplant Medicine 341
Gary G. Singer Immunosuppressive Medications 341
Rejection 343
Infectious Complications 345
Long-Term Complications 347
of Transplantation
Chandra Prakash ¦ / Gastrointestinal Diseases 349
Gastrointestinal Bleeding 349
Esophageal Disease 356
Peptic Ulcer Disease 359
Inflammatory Bowel Disease 362
Functional Gastrointestinal Disorders 364
- Acute Intestinal Pseudo- Obstruction (Ileus) 365
Pancreaticobiliary Disorders 366
Other Gastrointestinal Disorders 369
Dysphagia and Odynophagia 371
Nausea and Vomiting 372
Diarrhea 372
Constipation 374
Raj Satyanarayana and Mauricio Lisker-Melman 18 Liver Diseases Evaluation of Liver Function 376 376
Viral Hepatitis 378
Toxic and Drug-Related Liver Disease 384
Cholestatic Liver Disease 385
Metabolic Liver Disease 386
Miscellaneous Disorders 387
Complications of Hepatic Insufficiency 389
Liver Transplantation 392
Amir Tabatabai 19 Disorders of Hemostasis 394
Evaluation of Patients with Hemostatic Disorders 394
Platelet Disorders 397
Inherited Bleeding Disorders 403
Acquired Coagulation Disorders 405
Thromboembolic Disorders 406
Anticoagulants 410
Morey A. Blinder
Anémia and Transfusion 413
Therapy
Approach to the Patient with Anémia 413
Anemias Associated with Decreased 414
Red Blood Cell Production
Anemias Associated with Increased 421
Red Blood Cell Loss or Destruction
Transfusion Therapy 425
Joanne E. Mortimer and
Randy Brown
21
Medical Management
of Malignant Disease
Approach to the Cancer Patient
Complications of Cancer
Chemotherapy
Complications of Treatment
Hematopoietic Stem Cell
Transplantation
429
429
437
439
450
453
22
Sam Dagogo-Jack Diabetes Mellitus and 455
Related Disorders
Diabetes Mellitus 455
Diabetes Mellitus in 456
Hospitalized Patients
Type 1 Diabetes and 458
Diabetic Ketoacidosis
Type 2 Diabetes and Nonketotic 463
Hyperosmolar Syndrome
Diabetes Mellitus in 467
Surgical Patients
Chronic Complications 468
of Diabetes Mellitus
Hypoglycemia 470
23
William E. Clutter Endocrine Diseases 473
Evaluation of 473
Thyroid Function
Hypothyroidism 475
Hyperthyroidism 477
Euthyroid Goiter 481
Adrenal Failure 482
Cushing's Syndrome 484
Incidental Adrenal Nodules 484
Anterior Pituitary Gland Dysfunction 485
Metabolic Bone Disease 489
Leslie E. Kahl 24 Arthritis and Rheumatologic Diseases 491
Therapeutic Approaches to Rheumatic Disease 491
Approach to the Patient with a Single Painful Joint 501
Infectious Arthritis and Bursitis 501
Crystal-Induced Synovitis 503
Rheumatoid Arthritis 505
Osteoarthritis 507
Spondyloarthropathies 508
Systemic Lupus Erythematosus 510
Systemic Sclerosis 511
Necrotizing Vasculitis 512
Polymyalgia Rheumatica and Temporal Arteritis 514
Cryoglobulin Syndromes 514
Polymyositis and Dermatomyositis 514
Kelvin A. Yamada and Sylvia Awadalla 25 Neurologic Disorders Alterations in Consciousness 516 516
Seizures 521
Cerebrovascular Disease 523
Head Trauma 526
Acute Spinal Cord Dysfunction 528
Neuromuscular Disease 529
Headache 532
Dániel Goodenberger 26 Medical Emergencies 536
Acute Upper Airway Obstruction 536
Pneumothorax 537
Heat-Induced Illness 539
Cold-Induced Illness 541
xív Contents
Near-Drowning 543
Overdosage 544
Toxic Inhalants 573
Appendixes
Tom Daly A. Barnes-Jewish Hospitál Laboratory Reference Values 577
Lesley Ann Watson B. Pregnancy and Medical Therapeutics 584
S. Troy McMullin C. Drug Interactions 590
Robyn A. Schaiff D. Intravenous Admixture Preparation and Administration Guide 608
Way Y. Huey and Dániel W. Coyne E. Dosage Adjustments of Drugs in Renal Failure 611
Alexis M. Elward and Victoria J. Fraser F. Immunizations and Postexposure Therapies 619
Victoria J. Fraser and Alexis M. Elward G. Infection Control and Isolation Recommendations 624
Marin H. Kollef H. Critical Care Parameters and Formulas 627
Index
631

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