Role of Medroxyprogesterone in Endocrine-Related Tumors 3

Fülszöveg

Of Related Interest
L Campio, C. Robustelli Delia Cuna, and R. W Taylor, Editors
ROLE OF MEDROXYPROGESTERONE IN ENDOCRINE-RELATED TUMORS, VoL 2 230 pp. (1983) ISBN 0-89004-865-7 (Order Code 1211)
This volume explores the use of medroxyprogesterone acetate (MPA), a progestational agent whose importance in the treatment of several hormone-sensitive tumors derives from its multiple modes of action. The presentation covers three major areas: basics and rationale for the use of MPA; its use in the treatment of gynecological cancer and other urogenital tumors; and its value in treating breast cancer. Contributors discuss pharmacokinetics of the drug, its effects on tumor proliferation, combined antiestrogen-progestin therapy, the comparative effects of different dosage levels and combinations, and specific studies with several estrogen-sensitive tumor types.
This volume will be of interest to clinical oncologists, endocrinologists, gynecologists and urologists, and to biologists and... Tovább

Fülszöveg

Of Related Interest
L Campio, C. Robustelli Delia Cuna, and R. W Taylor, Editors
ROLE OF MEDROXYPROGESTERONE IN ENDOCRINE-RELATED TUMORS, VoL 2 230 pp. (1983) ISBN 0-89004-865-7 (Order Code 1211)
This volume explores the use of medroxyprogesterone acetate (MPA), a progestational agent whose importance in the treatment of several hormone-sensitive tumors derives from its multiple modes of action. The presentation covers three major areas: basics and rationale for the use of MPA; its use in the treatment of gynecological cancer and other urogenital tumors; and its value in treating breast cancer. Contributors discuss pharmacokinetics of the drug, its effects on tumor proliferation, combined antiestrogen-progestin therapy, the comparative effects of different dosage levels and combinations, and specific studies with several estrogen-sensitive tumor types.
This volume will be of interest to clinical oncologists, endocrinologists, gynecologists and urologists, and to biologists and pharmacologists involved in the development of new antitumor agents and the study of basic tumor cell function.
Helmut Creim, Reinhard Jung, Martin Kramer, Hans Marquardt, and Franz Oesch, Editors
BIOCHEMICAL BASIS OF CHEMICAL CARCINOGENESIS
(13th Workshop-Conference HOECHST)
328 pp., 99 illustrations (1984) I5BN 0-89004-961-0 (Order Code 1344)
This volume explores the various biochemical processes involved in chemical carcinogenesis. Major emphasis is placed on activation of chemical substances to toxic reactive metabolites and bindings of these metabolites to DNA and other critical targets within the cell. The authors highlight the many variable factors that determine carcinogenicity and mutagenicity, including the pattern of enzymes controlling the metabolism of a substance; the chemical nature and position of the DNA binding products; and the nature of the DNA repair process in a given organ. Other important topics covered include the relationship of oncogene activation to tumor initiation, the involvement of the products of oncogenes in carcinogenesis, and the molecular role of tumor promotion in carcinogenesis.
Biochemical Basis of Chemical Carcinogenesis will be of major significance to all cancer researchers, toxicologists, and industrial hygienists.
John D. Boice, Jr., and !oseph F. Fraumeni, jr., Editors
RADIATION CARCINOGENESIS: EPIDEMIOLOGY AND BIOLOGICAL
SIGNIFICANCE
(Progress in Cancer Research and Therapy, VoL 26) 510 pp. (1984) ISBN 0-89004-907-7 (Order Code 1289)
This timely volume provides a comprehensive overview of our current knowledge concerning radiation carcinogenesis. Leading investigators explore the relationship between radiation carcinogenesis and the mechanisms of human cancer development in general, and review both laboratory and epidemiological studies in the field. The book contributes in large measure to clarifying the ongoing controversy surrounding the carcinogenic risks of radiation exposure.
An introductory section provides an overview of epidemiological and experimental research to date. Following this are summaries of a number of recent epidemiological investigations in which either the whole body or parts of the body were exposed to radiation or to radioactive compounds. Readers will find entirely new information on • atomic bomb survivors • patients irradiated for cervical cancer, tuberculosis, ringworm of the scalp, gynecologic disease, and childhood cancer • the effects of prenatal irradiation. The book also covers dose-response relationships and induction periods in light of current findings. The authors close with an in-depth discussion of critical areas in need of further research.
Radiation Carcinogenesis is essential reading for oncologists, epidemiologists, radiation biologists, radiologists, and anyone concerned with the formulation of public and industrial health policy. It is a major synthesis of the data and theory on this vast and critical topic, and provides a comprehensive review of the fundamental processes involved in the development of a range of cancer types.
Raven Press 1140 Avenue of the Americas, New York, New York 10036 Vissza