Pathophysiology of Hypertension

Regulatory Mechanisms

Szerző

Szerkesztő

Amsterdam-New York

'M. J. Brody: Pathophysiology of Hypertension ' összes példány

Kiadó:	Elsevier
Kiadás helye:	Amsterdam-New York
Kiadás éve:	1986
Kötés típusa:	Fűzött keménykötés
Oldalszám:	703 oldal
Sorozatcím:	Handbook of Hypertension
Kötetszám:	8
Nyelv:	Angol
Méret:	25 cm x 17 cm
ISBN:	0-444-90422-0
Megjegyzés:	Fekete-fehér fotókkal, ábrákkal. További szerzők a könyvben.

Értesítőt kérek a kiadóról

Értesítőt kérek a sorozatról

A beállítást mentettük,
naponta értesítjük a beérkező friss
kiadványokról

Előszó

Foreword
The concept of the Handbook of Hypertension developed in the late 1970s from a widespread feeling that the diversity of interests and inputs into hypertension research did not lend themselves to publication in a single textbook. The Handbook of Hypertension has now come of age and is recognized as an authoritative source of information and reviews on clinical and research aspects of high blood pressure.
As we have previously observed, the scope of hypertension in man has developed over the last 30 years from the short-term care of a small number of hospitalized patients with severely elevated blood pressure and extensive target-organ failure to a major long-term community-health problem involving a substantial proportion of the population. It appeared possible at one time that the mechanisms involved in the pathogenesis of hypertension could be identified by a limited number of circumscript and straightforward experiments in laboratory animals. This is clearly not so. The field of experimental hypertension has, if anything, expanded even more than cHnical practice.
We shared with our Publishers the view that the accumulation of biological and clinical knowledge in the field of hypertension had outgrown the limitations of the classical monograph. Moreover, the subject of hypertension by its very nature is a multidisciplinary one, attracting such diverse professionals as biochemists and public health workers, in addition to clinicians. When one tries to envisage what would happen to a single all-encompassing book, it is clear that it could never satisfy the different groups involved in high blood pressure. Some sections would become outdated rapidly while others would have a longer life-span. An alternative, to escape from the constraints of a single textbook and to reconcile the interests of both generalists and speciaUsts, was to choose the format of a serial handbook.
The present work has resulted from lengthy deliberations and discussions with many clinicians and scientists. We believe that it will be of interest to many different groups including clinical investigators, house officers, general practitioners, biomedical students, pharmacologists, pharmacists, biological scientists, physiologists and epidemiologists.
In the overall design, three or perhaps four groups comprising 6 volumes each will be published. The first group was completed in 1985 (see page ii). The present volume on 'Pathophysiology of Hypertension — Regulatory Mechanisms' edited by Alberto Zanchetti and the late Robert Tarazi is the second of two volumes on Pathophysiology. The first, Volume 7, deals with Cardiovascular Aspects under the same Editorship. Listed below are the titles of further volumes currently in preparation. In addition, several volumes are under consideration and plans well advanced for the publication of revised or updated editions of earlier volumes:
Behavioral Aspects of Hypertension (Editor: S. Julius)
Hypertension during Pregnancy (Editor: P.C. Rubin)
Clinical Pharmacology — revised and updated (Editor: A.E. Doyle)
Clinical Aspects — revised and updated (Editor: J.I.S. Robertson)
Hypertension in the Elderly (Editors: A. Amery and J. Staessen)
Management of the Hypertensive Patient (Editors: F.R. Biihler and J.H. Laragh) Vissza

Tartalom

Contents
Foreword xv
W.H. Birkenhäger and J.L. Reid
Introduction xvii
A. Zanchetti
I. Neural mechanisms of cardiovascular regulation
1. Central neural control of the cardiovascular system 1
M.J. Brody, R.H. Aiper, T.P. O'Neill and J.P. Porter
2. Chemical messengers and transmitters in the brain and cardiovascular regulation 26
P.C. Luft, Th. Unger, R.E. Lang and D. Ganten
3. Reflex control of the circulation in experimental and human hypertension 47
G. Manda, A.U. Ferrari and A. Zanchetti
4. Positive feedback reflexes 69
A. Malliani, M. Pagani and P. Lombardi
5. Disorders of neural control of the cardiovascular system: clinical implications of cardiovascular reflexes 82
P. Sleight
6. Peripheral mechanisms in cardiovascular regulation: transmitters, receptors and the endothelium 96
P.M. Vanhoutte and T.P. Lüscher
7. a-Adrenoceptors and neural control of the circulation: studies in experimental animals 124
C.A. Hamilton, J. Vincent and J.L. Reid
8. Neural-renal interactions: physiological evidence 151
A. Zanchetti and A. Stella
9. Neural-renal interactions: evidence in experimental hypertension 173
S. Oparil, M.K. Donovan and J.M. Wyss
10. Sodium and adrenergic mechanisms 203
P. W. de Leeuw and W.H. Birkenhäger
11. Testing neural control of the circulation in patients: plasma catecholamines 216
M. Esler
12. Testing neural control of the circulation in patients: hemodynamic responses to exercise and stressful stimuh 237
5. Lundin, S. Jern and L. Hansson
xiii
Contents
13. Behavioral influences on blood pressure control: implications for the hypertensive process 250
P.A. Obrist, K.C. Light, A. Sherwood and M.T. Allen
II. Renal mechanisms of cardiovascular regulation
14. Sodium excretion and its role in blood pressure regulation 278
G. Bianchi
15. The pressure-diuresis-natriuresis mechanism in normal and hypertensive states 295
A.W. Cowley Jr and R.J. Roman
16. The biochemistry of renin 315
R. Day and E. Haber
17. The renin-angiotensin system: physiological regulation of renin release 365
A. Stella and A. Zanchetti
18. Angiotensin II: conformation and receptor interaction 389
R.B. Howard and R.R. Smeby
19. Physiological effects of angiotensins on the blood vessels and heart 398
T.L. Goodfriend
20. The brain renin-angiotensin system: pathways for angiotensin II formation in brain 421
A. Husain and R.B. Mojfett
21. The renin-angiotensin system: physiological actions on the central nervous system 431
C.M. Ferrario, Y. Ueno, D.I. Diz and K.L. Barnes
22. The renin-angiotensin system: physiological actions on the kidney 455
P.W. de Leeuw and W.H. Birkenhäger
23. The renin-angiotensin system: inhibitors and antagonists 466
K.G. Hoßauer and J.M. Wood
24. The renin-angiotensin system: role in experimental and human hypertension 489
B. Waeber, J. Nussberger and H.R. Brunner
25. Sensitivity to sodium and non-modulation of renal and adrenal responsiveness to angiotensin II: implications for the pathogenesis of essential hypertension 520
N.K. Hollenberg and G.H. Williams
26. The renal medullary system 553
E.E. Muirhead and J.A. Pitcock
XX
Contents IX
27. Eicosanoid-dependent mechanisms and the regulation of blood pressure 578
M.J.S. Miller, J. Quilley and J.C. McGiff
III. Hormones, ions and membranes in cardiovascular regulation
28. Aldosterone and other adrenal steroids 603
E.L. Bravo
29. Vasopressin 626
C.I. Johnston, M. Hiwatari, J. Abrahams, L. Arnolda and A. Culvenor
30. Atrial natriuretic factor 647
J. Genest and M. Cantin
31. The 'natriuretic hormone' and hypertension 658
H.E. de Wardener and G.A. MacGregor
32. Membrane markers of arterial hypertension 670
M. Baudouin-Legros, J.-F. Cloix, M. Crabos, G. Dagher, M. David-Dufilho, M.-A. Devynck, R.F. Garay, M.-L. Grichois, P. Guicheney, S. Koutouzov, P. Marche, M. de Mendonga, M.-G. Pernollet and P. Meyer
Index 687 - 703